rbsK [2017-8-11 16:0:3]

ribokinase

locus: BSU35920

pI: 4.61

mw: 30.99 kDa

protein length: 293 aa

gene length: 879 bp

function: ribose utilization

product: ribokinase

essential: no

ec: 2.7.1.15

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.4|Utilization of ribose]

Gene

Coordinates: 3,702,393 → 3,703,274

The protein

Catalyzed reaction/ biological activity

• ATP + D-ribose = ADP + D-ribose 5-phosphate (according to Swiss-Prot)

Protein family

• carbohydrate kinase pfkB family (according to Swiss-Prot)

Structure

• [PDB|1VM7] (the enzyme of ''Thermotoga maritima'', 38% identity)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|77AEAC0F06B4D5F062D4A2740794B7BFDDA31096|rbsR]-[gene|C229BD2C00B169CF4A99482E65B3F749AD9D51D8|rbsK]-[gene|F0E6F191FAF8F279462B09BF1FE4C6C752A57803|rbsD]-[gene|AB4A686F62550F90F5BD8D27DAADC9C33F1DA1DB|rbsA]-[gene|F1258E31151E137A850811B0C851D473CEFFD43B|rbsC]-[gene|1D67888E79B09956F9258F4068546D8C67103549|rbsB]
  description: [Pubmed|7921236]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|7511775], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

  regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|7921236], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: activation, [Pubmed|7592460], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

  regulation

  • expressed upon transition into the stationary phase ([protein|search|AbrB]) [Pubmed|7592460]

References

• 16872404,7511775,7592460,7921236